5 Best Laundry Detergents For Dog Urine

Peter Armani | 06-02-2026

Dog urine can leave behind persistent odors and stains on laundry, especially on pet bedding, blankets, and household fabrics. Choosing the right detergent is key to neutralizing smells and maintaining clean, fresh items for both you and your pets. This guide reviews several practical options designed to tackle dog urine in everyday laundry routines.

Editor's Choice
Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover
Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover
Premium Pick
KINZUA ENVIRONMENTAL Urine B-Gone Professional Enzyme Odor Eliminator
KINZUA ENVIRONMENTAL Urine B-Gone Professional Enzyme Odor Eliminator
Budget Pick
ACTIVE Enzyme-Based Pet Laundry Detergent Powder
ACTIVE Enzyme-Based Pet Laundry Detergent Powder

Top 5 Laundry Detergents For Dog Urine

We researched and compared the top products in the Laundry Detergents For Dog Urine category to provide you with these recommendations.

1. ACTIVE Enzyme-Based Pet Laundry Detergent Powder

Laundry Odor Removal
ACTIVE Enzyme-Based Pet Laundry Detergent Powder

This powder detergent feels concentrated and is often used for pet bedding, blankets, and clothing affected by urine odors. It's suitable for everyday laundry cycles and works with both pet-only and mixed loads. The fragrance-free formula is gentle on sensitive skin and doesn't cover up smells, but targets them directly.

What We Like:

  • Targets pet urine and tough odors
  • Works on many fabric types
  • Fragrance-free and gentle
  • Compatible with HE and standard washers
  • Can be used as a pre-soak

What Could Be Improved:

  • Powder may need extra dissolving in cold water
  • Pre-soaking required for heavy soiling

2. Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover

Laundry Enzyme Formula
Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover
9.8

Nature's Miracle

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This liquid additive blends easily with your regular detergent, making it a simple upgrade for routine laundry cycles. The formula feels gentle on most fabrics and is commonly used on pet bedding, clothing, and washable household items. It’s designed for everyday practicality, helping to address tough pet stains and odors without harsh chemicals.

What We Like:

  • Breaks down common pet stains and odors
  • Works with standard and HE machines
  • Free from phosphates and bleach
  • Gentle for use around pets
  • Easy to add to any wash load

What Could Be Improved:

  • Not suitable for all specialty fabrics
  • May require multiple washes for heavy soiling

3. LaundraPet 3X Strength Premium Laundry Detergent with Enzyme Cleaner

Triple Enzyme Action
LaundraPet 3X Strength Premium Laundry Detergent with Enzyme Cleaner

This liquid detergent offers a concentrated feel and is formulated for pet-related laundry, including urine and heavy soils. It's often chosen for its compatibility with high-efficiency machines and its ability to handle larger loads. The enzyme-based formula is designed to break down organic stains and odors while being gentle on fabrics.

What We Like:

  • Triple enzyme cleaning power
  • Suitable for large or frequent loads
  • Works in cold water cycles
  • Gentle on most fabrics
  • Designed for pet-specific soils

What Could Be Improved:

  • Scent may be noticeable to sensitive pets
  • May require extra rinse for thick fabrics

4. Bark2Basics Dog-Off Laundry Liquid Detergent

Pet Safe Formula
Bark2Basics Dog-Off Laundry Liquid Detergent
8.9

Bark2basics

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This liquid detergent is made with naturally derived, concentrated ingredients and is commonly used for washing towels, clothing, and bedding for pets. Its formula is designed to be gentle and safe for use around dogs and cats, making it a practical choice for pet households. The large bottle is intended for frequent washes and offers a biodegradable option for eco-conscious users.

What We Like:

  • Safe for a variety of pet items
  • Biodegradable and concentrated
  • Suitable for frequent laundry needs
  • Developed by grooming industry experts

What Could Be Improved:

  • No included scoop or cup
  • Liquid format may be less convenient for some users

5. KINZUA ENVIRONMENTAL Urine B-Gone Professional Enzyme Odor Eliminator

Deep Enzyme Cleaning
KINZUA ENVIRONMENTAL Urine B-Gone Professional Enzyme Odor Eliminator
9.1

Kinzua Environmental

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This liquid enzyme cleaner offers a thorough cleaning experience, especially for homes dealing with persistent pet odors. It’s commonly used on carpets, upholstery, and even laundry, making it versatile for more than just floors. The mild lavender fragrance provides a fresh touch without overpowering the space.

What We Like:

  • Penetrates deep to target tough odors
  • Suitable for multiple surfaces
  • Can be used in laundry or drains
  • Safe for pets when used as directed
  • Subtle lavender scent

What Could Be Improved:

  • May require extra time for full odor removal
  • Liquid application can be less convenient than sprays

How to Choose Laundry Detergents for Dog Urine

Enzyme detergents are especially effective at breaking down organic stains and odors left by dog urine. Make sure the product is safe for your fabrics and fits your laundry routine.

Enzyme Power and Odor Removal

Enzyme cleaners are preferred for persistent urine smells, as they work at a molecular level to neutralize odors.

Fabric and Pet Safety

Pet-safe detergents help prevent skin irritation and are better for items your dog frequently touches.

Machine Compatibility and Application

Choose a format that fits your washer and laundry habits. Additives can boost your regular detergent, while dedicated pet detergents may replace it entirely.

Scent Preferences

Some households prefer no added fragrance to avoid overwhelming pets, while others like a subtle fresh scent after washing.

Practical Usage Tips

Pre-soaking and following label directions can improve results, especially with strong urine odors or older stains.

FAQ For Laundry Detergents For Dog Urine

1. Why are enzyme-based detergents recommended for dog urine?

Enzyme-based detergents are effective because they break down the proteins and organic compounds in dog urine, helping to neutralize both stains and odors at the source.

2. Can I use regular laundry detergent to remove dog urine odors?

Regular detergents may clean visible stains but often struggle to fully remove urine odors. Specialized formulas with enzymes are more effective for persistent smells.

3. Are these detergents safe for washing pet bedding and toys?

Most pet-specific detergents are formulated to be gentle and safe for washing pet bedding, blankets, and washable toys. Always check the label for fabric compatibility and safety notes.

4. Is it necessary to pre-soak items with dog urine stains?

Pre-soaking can help loosen and break down tough urine stains and odors, especially on heavily soiled items. This step is often recommended for best results.

5. Do scented detergents help mask dog urine odors?

Scented detergents may provide a fresh smell, but enzyme-based formulas are more effective at neutralizing odors rather than just masking them.
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Peter Armani

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